50-52-2 MSDS - Thioridazine
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Thioridazine

Identification
Name Thioridazine
CAS Registry Number 50-52-2
Synonyms THIORIDAZINE;10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin;10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin;10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin;10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine;10-[2-(1-Methyl-2-piperdiyl)ethyl]-2-(methylthio)phenothiazine;10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine;10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-
Molecular Structure Thioridazine   50-52-2
Molecular Formula C21H26N2S2
Molecular Weight 370.57
Supplier
Lightchem Inc
Supply Precious metal catalyst
OLED Materials etc.
www.lightchem.com
 
Wiki & MSDS
50-52-2.pdf
Thioridazine
Thioridazine.svg
Clinical data
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a682119
License data
  • US DailyMed: 9c4bedb4-2d59-4fcd-aad7-fce988cd96d8
  • US FDA: Thioridazine
Pregnancy
category
  • AU: C
  • US: C (Risk not ruled out)
Routes of
administration
Oral
ATC code
  • N05AC02 (WHO)
Legal status
Legal status
  • Withdrawn by the manufacturer worldwide[1]
Pharmacokinetic data
Bioavailability incomplete
Metabolism hepatic (at least partly mediated by CYP2D6)
Biological half-life 21-24 hours[2]
Excretion faeces
Identifiers
CAS Number
  • 50-52-2 YesY
PubChem CID
  • 5452
IUPHAR/BPS
  • 100
DrugBank
  • DB00679 YesY
ChemSpider
  • 5253 YesY
UNII
  • N3D6TG58NI
KEGG
  • D00373 YesY
ChEBI
  • CHEBI:9566 YesY
ChEMBL
  • CHEMBL479 YesY
ECHA InfoCard 100.000.041
Chemical and physical data
Formula C21H26N2S2
Molar mass 370.577
3D model (Jmol)
  • Interactive image
  (verify)

Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis; the branded product was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias, however, generic versions are available in the US.[1]


 







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